Analgesic benefits were achieved over time. Static magnetic fields can penetrate up to 20mm and appear to target the ectopic firing nociceptors in the epidermis and dermis. For a subset of patients with baseline severe pain, statistically significant reductions occurred from baseline through the fourth month in numbness and tingling (magnet, -32% sham, -14% P<.01, ANOVA) and foot pain (magnet, -41% sham, -21% P<.01, ANOVA). There were statistically significant reductions during the third and fourth months in burning (mean change for magnet treatment, -12% for sham, -3% P<.05, ANCOVA), numbness and tingling (magnet, -10% sham, +1% P<.05, ANCOVA), and exercise-induced foot pain (magnet, -12% sham, -4% P<.05, ANCOVA). Steven Cole-Schwartz is a Director, Portfolio at Group Health Foundation based in Seattle, Washington. Analysis of variance (ANOVA), analysis of covariance (ANCOVA), and chi-square analysis were performed. Secondary measures included nerve conduction changes, role of placebo, and safety issues. Nerve conduction and/or quantified sensory testing were performed serially.ĭaily visual analog scale scores for numbness or tingling and burning and QOL issues were tabulated over 4 months. Three hundred seventy-five subjects with DPN stage II or III were randomly assigned to wear constantly magnetized insoles for 4 months the placebo group wore similar, unmagnetized device. Randomized, placebo-control, parallel study. To determine if constant wearing of multipolar, static magnetic (450G) shoe insoles can reduce neuropathic pain and quality of life (QOL) scores in symptomatic diabetic peripheral neuropathy (DPN).
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